What are the Subclades of Haplogroup E?
Y-chromosome Haplogroup E originated in Africa and is an early branch of the Y-chromosome lineage. Only three variations of the Y-chromosome separate it from the founding Y-chromosome Haplogroup A , aka ‘Y-DNA Adam’. Haplogroup E is abundant in all regions in Africa and in some populations it makes up nearly 100% of the Y-chromosomes. It is a highly diversified haplogroup with many subclades that have unique histories and distributions, including regions outside of Africa in nearby Asia and Europe. Haplogroup E and its subclades encompass episodes from early Stone Age migrations to the spread of Bantu farmers 2,000-4,000 years ago to recent slave-trading in the 19th century that brought men with this haplogroup to the New World.
The following diagram depicts the current, deeply branching phylogenetic tree for Y-chromosome Haplogroup E. This haplogroup has many subclades and while most of the information on subclades is based on studies in African populations, the haplogroup is also found parts of in Eurasia.

Description of the panel
The current version of the Y-DNA Haplogroup E Subclade Test now consists of a panel of 48 SNP markers. These markers are used to define the 47 different subclades in Haplogroup E. The location of the SNP, the actual mutation that is detected, and the subclade that they define is listed below for each of the markers in the panel.
|
Location of SNP |
SNP |
Haplogroup E subclade |
|
|
|
M40 |
G > A |
E |
|
|
|
M132 |
G > T |
E1a |
|
|
|
M44 |
G > C |
E1a1 |
|
P2 |
C > T |
E1b1 |
|
M2 |
A > G |
E1b1a |
|
M58 |
G > A |
E1b1a1 |
E1b1a |
E1 |
|
M116.2 |
A > C |
E1b1a2 |
|
M149 |
G > A |
E1b1a3 |
|
M154 |
T > C |
E1b1a4 |
|
M155 |
G > A |
E1b1a5 |
|
M10 |
T > C |
E1b1a6 |
|
M191 |
T > G |
E1b1a7 |
|
U174 |
G > A |
E1b1a7a |
|
U175 |
G > A |
E1b1a8 |
|
U209 |
C > T |
E1b1a8a |
|
U290 |
T > A |
E1b1a8a1 |
|
U181 |
C > T |
E1b1a8a1a |
|
P59 |
A > G |
E1b1a8a2 |
|
P268 |
T > A |
E1b1a9 |
|
M215 |
A > G |
E1b1b |
E1b1b |
|
M35 |
G > C |
E1b1b1 |
|
M78 |
C > T |
E1b1b1a |
|
V12 |
A > G |
E1b1b1a1 |
|
M224 |
T > C |
E1b1b1a1a |
|
V32 |
G > C |
E1b1b1a1b |
|
V13 |
G > C |
E1b1b1a2 |
|
V27 |
A > T |
E1b1b1a2a |
|
V22 |
T > C |
E1b1b1a3 |
|
M148 |
A > G |
E1b1b1a3a |
|
V19 |
T > C |
E1b1b1a3b |
|
V65 |
G > T |
E1b1b1a4 |
|
M81 |
C > T |
E1b1b1b |
|
M107 |
A > G |
E1b1b1b1 |
|
M183 |
A > C |
E1b1b1b2 |
|
M165 |
A > G |
E1b1b1b2a |
|
M123 |
G > A |
E1b1b1c |
|
M34 |
G > T |
E1b1b1c1 |
|
M84 |
A del |
E1b1b1c1a |
|
M290 |
C > T |
E1b1b1c1b |
|
M281 |
G > A |
E1b1b1d |
|
V6 |
G > C |
E1b1b1e |
|
M329 |
G > C |
E1b1c |
|
|
|
P75 |
G > A |
E1b2 |
|
M75 |
G > A |
E2 |
E2 |
|
|
M41 |
G > T |
E2a |
|
|
M54 |
G > A |
E2b |
|
|
M85 |
C > A |
E2b1 |
|
|
M200 |
G > A |
E2b1a |
|