Jul 07 2008
Which markers are tested in the mtDNA SNP Haplogroup H Subclade Test Panel?
The mtDNA SNP Haplogroup H Subclade Test Panel examines 17 unique SNP markers in the coding region of the mtDNA. These 17 SNP markers define up to 16 different subclades of Haplogroup H (Subclades 1 to 16). The chart below lists the 17 SNP markers that are included in this panel and the Subclades that they define.
| SNP Location | Mutations | Subclades of H |
|---|---|---|
| 1438 | A > G | Excludes H2 |
| 2259 | C > T | H13 |
| 3010 | G > A | H1 |
| 3915 | G > A | H6 |
| 3936 | C > T | H12 |
| 3992 | C > T | H4 |
| 4310 | A > G | H9 |
| 4336 | T > C | H5a |
| 4769 | A > G | Excludes H2a |
| 4793 | A > G | H7 |
| 6253 | T > C | H15 |
| 6776 | T > C | H3 |
| 8448 | T > C | H11 |
| 10394 | C > T | H16 |
| 11377 | G > A | H14 |
| 13101 | A > C | H8 |
| 14470 | T > A | H10 |
The diagram below is a phylogenetic tree illustrating the various subclades of H that are known. The diagram also shows where each of the 17 SNP fall in the tree. Click here to download a detailed copy of the Haplogroup H Subclade Map.
